Contribution of the C-8 substituent of DU-6859a, a new potent fluoroquinolone, to its activity against DNA gyrase mutants of Pseudomonas aeruginosa.

Inhibitory effects of five quinolones against DNA gyrases purified from four quinolone-resistant clinical isolates of Pseudomonas aeruginosa and the quinolone-susceptible strain PAO1 were examined. All of the quinolone-resistant strains tested were found to be DNA gyrase mutants. The 50% inhibitory...

Full description

Saved in:
Bibliographic Details
Main Authors: Kitamura, A, Hoshino, K, Kimura, Y, Hayakawa, I, Sato, K
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC162764/
https://ncbi.nlm.nih.gov/pubmed/7492087
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items