Response of rat model of Pneumocystis carinii pneumonia to continuous infusion of deferoxamine.
The iron-chelating drug deferoxamine mesylate (DFO) is active against Pneumocystis carinii in vitro and in rat and mouse models of P. carinii pneumonia. Because DFO has a short half-life, daily divided or continuous dosage was expected to improve the dose response, as is the case with DFO treatment...
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| Опубликовано в:: | Antimicrob Agents Chemother |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
1995
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162759/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7492082/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.7.1442 |
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