Response of rat model of Pneumocystis carinii pneumonia to continuous infusion of deferoxamine.

The iron-chelating drug deferoxamine mesylate (DFO) is active against Pneumocystis carinii in vitro and in rat and mouse models of P. carinii pneumonia. Because DFO has a short half-life, daily divided or continuous dosage was expected to improve the dose response, as is the case with DFO treatment...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Merali, S, Chin, K, Grady, R W, Weissberger, L, Clarkson, A B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162759/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7492082/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.7.1442
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