Use of 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil as a novel antiviral agent for hepatitis B virus and Epstein-Barr virus.

A novel anti-hepatitis B virus (anti-HBV) agent, 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil (L-FMAU), was synthesized and found to be a potent anti-HBV and anti-Epstein-Barr virus agent. Its in vitro potency was evaluated in 2.2.15 and H1 cells for anti-HBV and anti-Epstein-Barr virus activiti...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Chu, C K, Ma, T, Shanmuganathan, K, Wang, C, Xiang, Y, Pai, S B, Yao, G Q, Sommadossi, J P, Cheng, Y C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162665/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7786007/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.4.979
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