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In vitro evaluation of ABT-719, a novel DNA gyrase inhibitor.

ABT-719 (A-86719.1) is the first compound of a new class of novel DNA gyrase inhibitors, the 2-pyridones, with potent antibacterial activity against gram-positive, gram-negative, and anaerobic organisms. ABT-719 was more active than ciprofloxacin, sparfloxacin, and clinafloxacin against gram-positiv...

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Autori principali: Flamm, R K, Vojtko, C, Chu, D T, Li, Q, Beyer, J, Hensey, D, Ramer, N, Clement, J J, Tanaka, S K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC162662/
https://ncbi.nlm.nih.gov/pubmed/7786004
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