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Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70

Heat shock proteins 70 (hsp70) derived from tissues and cells can elicit cytotoxic T lymphocyte (CTL) responses against peptides bound to hsp70. However, peptides can markedly differ in their affinity for hsp, and this potentially limits the repertoire of peptides available to induce CTL by the hsp...

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Main Authors: Moroi, Yoichi, Mayhew, Mark, Trcka, Jiri, Hoe, Mee H., Takechi, Yoshizumi, Hartl, F. Ulrich, Rothman, James E., Houghton, Alan N.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC16266/
https://ncbi.nlm.nih.gov/pubmed/10725409
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