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CD80 cytoplasmic domain controls localization of CD28, CTLA-4 and PKC-θ in the immunological synapse
Co-stimulatory ligand CD80 interaction with CD28 or CTLA-4 plays an important role in the regulation of the T cell response. We have examined the role of the cytoplasmic domain of CD80 in murine T cell co-stimulation and its organization in the immunological synapse (IS). When compared to the wild t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1626532/ https://ncbi.nlm.nih.gov/pubmed/16339518 |
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