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T cell-dendritic cell immunological synapses contain TCR dependent CD28-CD80 clusters that recruit protein kinase C-θ
Short-lived TCR microclusters and a longer-lived protein kinase C-θ (PKC-θ) focusing central supramolecular activation cluster (cSMAC) have been defined in model immunological synapses (IS). In different model systems, CD28 mediated costimulatory interactions have been detected in microclusters, the...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556893/ https://ncbi.nlm.nih.gov/pubmed/18802089 |
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