T cell-dendritic cell immunological synapses contain TCR dependent CD28-CD80 clusters that recruit protein kinase C-θ

Short-lived TCR microclusters and a longer-lived protein kinase C-θ (PKC-θ) focusing central supramolecular activation cluster (cSMAC) have been defined in model immunological synapses (IS). In different model systems, CD28 mediated costimulatory interactions have been detected in microclusters, the...

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Bibliographic Details
Main Authors: Tseng, Su-Yi, Waite, Janelle C., Liu, Mengling, Vardhana, Santosha, Dustin, Michael L.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556893/
https://ncbi.nlm.nih.gov/pubmed/18802089
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