EC(5)S Ubiquitin Complex Is Recruited by KSHV Latent Antigen LANA for Degradation of the VHL and p53 Tumor Suppressors

Cellular protein degradation pathways can be utilized by viruses to establish an environment that favors their propagation. Here we report that the Kaposi's sarcoma–associated herpesvirus (KSHV)-encoded latency-associated nuclear antigen (LANA) directly functions as a component of the EC(5)S ub...

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Detaylı Bibliyografya
Asıl Yazarlar: Cai, Qi-Liang, Knight, Jason S, Verma, Suhbash C, Zald, Philip, Robertson, Erle S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2006
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1626105/
https://ncbi.nlm.nih.gov/pubmed/17069461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0020116
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