Pharmacokinetics and tissue penetration of the new fluoroquinolone grepafloxacin.
A single 400-mg oral dose of grepafloxacin (OPC-17116) was given to each of six healthy male volunteers, and the concentrations of the drug in plasma, cantharides-induced inflammatory fluid, and urine were measured over the subsequent 12 h. The mean peak concentration in plasma of 1.5 micrograms/ml...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7726523/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.2.513 |
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