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Pharmacokinetics and tissue penetration of the new fluoroquinolone grepafloxacin.

A single 400-mg oral dose of grepafloxacin (OPC-17116) was given to each of six healthy male volunteers, and the concentrations of the drug in plasma, cantharides-induced inflammatory fluid, and urine were measured over the subsequent 12 h. The mean peak concentration in plasma of 1.5 micrograms/ml...

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Publicado en:Antimicrob Agents Chemother
Principais autores: Child, J, Andrews, J M, Wise, R
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1995
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162569/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7726523/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.2.513
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