Pharmacokinetics and tissue penetration of the new fluoroquinolone grepafloxacin.

A single 400-mg oral dose of grepafloxacin (OPC-17116) was given to each of six healthy male volunteers, and the concentrations of the drug in plasma, cantharides-induced inflammatory fluid, and urine were measured over the subsequent 12 h. The mean peak concentration in plasma of 1.5 micrograms/ml...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Child, J, Andrews, J M, Wise, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7726523/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.2.513
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