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Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice

Motor incoordination, immune deficiencies, and an increased risk of cancer are the characteristic features of the hereditary disease ataxia–telangiectasia (A-T), which is caused by mutations in the ATM gene. Through gene targeting, we have generated a line of Atm mutant mice, Atm(y/y) mice. In contr...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Borghesani, Paul R., Alt, Frederick W., Bottaro, Andrea, Davidson, Laurie, Aksoy, Saime, Rathbun, Gary A., Roberts, Thomas M., Swat, Wojciech, Segal, Rosalind A., Gu, Yansong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2000
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16240/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716718/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050584897
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