Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice

Motor incoordination, immune deficiencies, and an increased risk of cancer are the characteristic features of the hereditary disease ataxia–telangiectasia (A-T), which is caused by mutations in the ATM gene. Through gene targeting, we have generated a line of Atm mutant mice, Atm(y/y) mice. In contr...

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出版年:	Proc Natl Acad Sci U S A
主要な著者:	Borghesani, Paul R., Alt, Frederick W., Bottaro, Andrea, Davidson, Laurie, Aksoy, Saime, Rathbun, Gary A., Roberts, Thomas M., Swat, Wojciech, Segal, Rosalind A., Gu, Yansong
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 2000
主題:	Biological Sciences
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16240/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716718/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050584897
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