Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice

Motor incoordination, immune deficiencies, and an increased risk of cancer are the characteristic features of the hereditary disease ataxia–telangiectasia (A-T), which is caused by mutations in the ATM gene. Through gene targeting, we have generated a line of Atm mutant mice, Atm(y/y) mice. In contr...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Borghesani, Paul R., Alt, Frederick W., Bottaro, Andrea, Davidson, Laurie, Aksoy, Saime, Rathbun, Gary A., Roberts, Thomas M., Swat, Wojciech, Segal, Rosalind A., Gu, Yansong
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2000
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16240/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716718/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050584897
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