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Multiple roles of Rev3, the catalytic subunit of polζ in maintaining genome stability in vertebrates

Translesion DNA synthesis (TLS) and homologous DNA recombination (HR) are two major postreplicational repair (PRR) pathways. The REV3 gene of Saccharomyces cerevisiae encodes the catalytic subunit of DNA polymerase ζ, which is involved in mutagenic TLS. To investigate the role of REV3 in vertebrates...

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Udgivet i:EMBO J
Principais autores: Sonoda, Eiichiro, Okada, Takashi, Zhao, Guang Yu, Tateishi, Satoshi, Araki, Kasumi, Yamaizumi, Masaru, Yagi, Takashi, Verkaik, Nicole S., van Gent, Dik C., Takata, Minoru, Takeda, Shunichi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2003
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162160/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12805232/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg308
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