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Multiple roles of Rev3, the catalytic subunit of polζ in maintaining genome stability in vertebrates
Translesion DNA synthesis (TLS) and homologous DNA recombination (HR) are two major postreplicational repair (PRR) pathways. The REV3 gene of Saccharomyces cerevisiae encodes the catalytic subunit of DNA polymerase ζ, which is involved in mutagenic TLS. To investigate the role of REV3 in vertebrates...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC162160/ https://ncbi.nlm.nih.gov/pubmed/12805232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg308 |
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