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Phospholipase Cδ(1) is required for skin stem cell lineage commitment

Phosphoinositide-specific phospholipase C (PLC) is a key enzyme in phosphoinositide turnover and is involved in a variety of physiological functions. Here we report that PLCδ(1)-deficient mice undergo progressive hair loss in the first postnatal hair cycle. Epidermal hyperplasia was observed, and ma...

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Detalhes bibliográficos
Main Authors: Nakamura, Yoshikazu, Fukami, Kiyoko, Yu, Haiyan, Takenaka, Kei, Kataoka, Yuki, Shirakata, Yuji, Nishikawa, Shin-Ichi, Hashimoto, Koji, Yoshida, Nobuaki, Takenawa, Tadaomi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC162154/
https://ncbi.nlm.nih.gov/pubmed/12805213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg302
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