Simultaneous loss of phospholipase Cδ1 and phospholipase Cδ3 causes cardiomyocyte apoptosis and cardiomyopathy

Phospholipase C (PLC) is a key enzyme in phosphoinositide turnover. Among 13 PLC isozymes, PLCδ1 and PLCδ3 share high sequence homology and similar tissue distribution, and are expected to have functional redundancy in many tissues. We previously reported that the simultaneous loss of PLCδ1 and PLCδ...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Nakamura, Y, Kanemaru, K, Kojima, R, Hashimoto, Y, Marunouchi, T, Oka, N, Ogura, T, Tanonaka, K, Fukami, K
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2014
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047916/
https://ncbi.nlm.nih.gov/pubmed/24810051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.181
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