Functional neuroimaging of cognition impaired by a classical antihistamine, d-chlorpheniramine

1. Antihistamine induced cognitive decline was evaluated using positron emission tomography (PET) measurement of histamine H1 receptor (H1R) occupancy and regional cerebral blood flow (rCBF). 2. Cognitive performance in attention-demanding task deteriorated dose-dependently and the effects were stat...

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Main Authors: Okamura, Nobuyuki, Yanai, Kazuhiko, Higuchi, Makoto, Sakai, Jun, Iwata, Ren, Ido, Tatsuo, Sasaki, Hidetada, Watanabe, Takehiko, Itoh, Masatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1621119/
https://ncbi.nlm.nih.gov/pubmed/10694210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702994
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