Construction and Characterization of a Pseudomonas aeruginosa Mucoid Exopolysaccharide-Alginate Conjugate Vaccine

Deterioration of lung function in patients with cystic fibrosis (CF) is closely associated with chronic pulmonary infection with mucoid Pseudomonas aeruginosa. The mucoid exopolysaccharide (MEP) from P. aeruginosa has been shown to induce opsonic antibodies in mice that are protective against this c...

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Bibliografiske detaljer
Main Authors: Theilacker, Christian, Coleman, Fadie T., Mueschenborn, Simone, Llosa, Nicolas, Grout, Martha, Pier, Gerald B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC162014/
https://ncbi.nlm.nih.gov/pubmed/12819072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.7.3875-3884.2003
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