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Construction and Characterization of a Pseudomonas aeruginosa Mucoid Exopolysaccharide-Alginate Conjugate Vaccine

Deterioration of lung function in patients with cystic fibrosis (CF) is closely associated with chronic pulmonary infection with mucoid Pseudomonas aeruginosa. The mucoid exopolysaccharide (MEP) from P. aeruginosa has been shown to induce opsonic antibodies in mice that are protective against this c...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Theilacker, Christian, Coleman, Fadie T., Mueschenborn, Simone, Llosa, Nicolas, Grout, Martha, Pier, Gerald B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2003
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12819072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.7.3875-3884.2003
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