Construction and Characterization of a Pseudomonas aeruginosa Mucoid Exopolysaccharide-Alginate Conjugate Vaccine

Deterioration of lung function in patients with cystic fibrosis (CF) is closely associated with chronic pulmonary infection with mucoid Pseudomonas aeruginosa. The mucoid exopolysaccharide (MEP) from P. aeruginosa has been shown to induce opsonic antibodies in mice that are protective against this c...

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Bibliographische Detailangaben
Hauptverfasser: Theilacker, Christian, Coleman, Fadie T., Mueschenborn, Simone, Llosa, Nicolas, Grout, Martha, Pier, Gerald B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC162014/
https://ncbi.nlm.nih.gov/pubmed/12819072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.7.3875-3884.2003
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