Construction and Characterization of a Pseudomonas aeruginosa Mucoid Exopolysaccharide-Alginate Conjugate Vaccine

Deterioration of lung function in patients with cystic fibrosis (CF) is closely associated with chronic pulmonary infection with mucoid Pseudomonas aeruginosa. The mucoid exopolysaccharide (MEP) from P. aeruginosa has been shown to induce opsonic antibodies in mice that are protective against this c...

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Autors principals: Theilacker, Christian, Coleman, Fadie T., Mueschenborn, Simone, Llosa, Nicolas, Grout, Martha, Pier, Gerald B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC162014/
https://ncbi.nlm.nih.gov/pubmed/12819072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.7.3875-3884.2003
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