The Largest Open Reading Frame (pks12) in the Mycobacterium tuberculosis Genome Is Involved in Pathogenesis and Dimycocerosyl Phthiocerol Synthesis

The cell wall lipids in Mycobacterium tuberculosis are probably involved in pathogenesis. The largest open reading frame in the genome of M. tuberculosis H37Rv, pks12, is unique in that it encodes two sets of domains needed to produce fatty acids. A pks12-disrupted mutant was produced, and disruptio...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Sirakova, Tatiana D., Dubey, Vinod S., Kim, Hwa-Jung, Cynamon, Michael H., Kolattukudy, Pappachan E.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Bacterial Infections
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161999/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12819062/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.7.3794-3801.2003
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!