Vaccine Efficacy of a Lysine Auxotroph of Mycobacterium tuberculosis

The in vivo growth phenotype and vaccine efficacy of a lysine auxotrophic mutant of Mycobacterium tuberculosis strain H37Rv are described. An immunization experiment using a mouse model with an aerosol challenge showed that two doses of the M. tuberculosis mutant were required to generate protection...

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Bibliografiset tiedot
Päätekijät: Pavelka, Martin S., Chen, Bing, Kelley, Cynthia L., Collins, Frank M., Jacobs, William R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2003
Aiheet:
Microbial Immunity and Vaccines
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC161997/
https://ncbi.nlm.nih.gov/pubmed/12819116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.7.4190-4192.2003
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