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Vaccine Efficacy of a Lysine Auxotroph of Mycobacterium tuberculosis
The in vivo growth phenotype and vaccine efficacy of a lysine auxotrophic mutant of Mycobacterium tuberculosis strain H37Rv are described. An immunization experiment using a mouse model with an aerosol challenge showed that two doses of the M. tuberculosis mutant were required to generate protection...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC161997/ https://ncbi.nlm.nih.gov/pubmed/12819116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.7.4190-4192.2003 |
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