Disruption of the ICOS-B7RP-1 Costimulatory Pathway Leads to Enhanced Hepatic Immunopathology and Increased Gamma Interferon Production by CD4 T Cells in Murine Schistosomiasis

Morbidity and mortality in schistosomiasis are largely due to an immune response mediated by CD4 T lymphocytes. Since lymphocyte activation is shaped by costimulatory signals, the specific functions of different costimulatory pathways are of increasing interest. We now examined the role of the induc...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Rutitzky, Laura I., Özkaynak, Engin, Rottman, James B., Stadecker, Miguel J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Fungal and Parasitic Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC161982/
https://ncbi.nlm.nih.gov/pubmed/12819093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.7.4040-4044.2003
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares