Interleukin-12- and Gamma Interferon-Dependent Protection against Malaria Conferred by CpG Oligodeoxynucleotide in Mice

Unmethylated CpG dinucleotides in bacterial DNA or synthetic oligodeoxynucleotides (ODNs) cause B-cell proliferation and immunoglobulin secretion, monocyte cytokine secretion, and activation of natural killer (NK) cell lytic activity and gamma interferon (IFN-γ) secretion in vivo and in vitro. The p...

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Detalhes bibliográficos
Main Authors: Gramzinski, Robert A., Doolan, Denise L., Sedegah, Martha, Davis, Heather L., Krieg, Arthur M., Hoffman, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98068/
https://ncbi.nlm.nih.gov/pubmed/11179339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1643-1649.2001
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