Accuracy of thymine–thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase η

The Saccharomyces cerevisiae RAD30 gene functions in error-free replication of UV-damaged DNA. RAD30 encodes a DNA polymerase, Pol η, which inserts two adenines opposite the two thymines of a cis-syn thymine–thymine (T–T) dimer. Here we use steady-state kinetics to determine the accuracy of DNA synt...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Washington, M. Todd, Johnson, Robert E., Prakash, Satya, Prakash, Louise
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 2000
主題:	Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16198/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10725365/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050491997
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