Accuracy of thymine–thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase η
The Saccharomyces cerevisiae RAD30 gene functions in error-free replication of UV-damaged DNA. RAD30 encodes a DNA polymerase, Pol η, which inserts two adenines opposite the two thymines of a cis-syn thymine–thymine (T–T) dimer. Here we use steady-state kinetics to determine the accuracy of DNA synt...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16198/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10725365/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050491997 |
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