Unambiguous demonstration of triple-helix-directed gene modification

Triple-helix-forming oligonucleotides (TFOs), which can potentially modify target genes irreversibly, represent promising tools for antiviral therapies. However, their effectiveness on endogenous genes has yet to be unambiguously demonstrated. To monitor endogenous gene modification by TFOs in a yea...

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Bibliographic Details
Main Authors: Barre, François-Xavier, Ait-Si-Ali, Slimane, Giovannangeli, Carine, Luis, Richard, Robin, Philippe, Pritchard, Linda L., Hélène, Claude, Harel-Bellan, Annick
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC16196/
https://ncbi.nlm.nih.gov/pubmed/10716704
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