Unambiguous demonstration of triple-helix-directed gene modification

Triple-helix-forming oligonucleotides (TFOs), which can potentially modify target genes irreversibly, represent promising tools for antiviral therapies. However, their effectiveness on endogenous genes has yet to be unambiguously demonstrated. To monitor endogenous gene modification by TFOs in a yea...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Barre, François-Xavier, Ait-Si-Ali, Slimane, Giovannangeli, Carine, Luis, Richard, Robin, Philippe, Pritchard, Linda L., Hélène, Claude, Harel-Bellan, Annick
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16196/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716704/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050368997
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