Unambiguous demonstration of triple-helix-directed gene modification

Triple-helix-forming oligonucleotides (TFOs), which can potentially modify target genes irreversibly, represent promising tools for antiviral therapies. However, their effectiveness on endogenous genes has yet to be unambiguously demonstrated. To monitor endogenous gene modification by TFOs in a yea...

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Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Barre, François-Xavier, Ait-Si-Ali, Slimane, Giovannangeli, Carine, Luis, Richard, Robin, Philippe, Pritchard, Linda L., Hélène, Claude, Harel-Bellan, Annick
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2000
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16196/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716704/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050368997
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