HuR binding to cytoplasmic mRNA is perturbed by heat shock
AU-rich elements (AREs) located in the 3′ untranslated region target the mRNAs encoding many protooncoproteins, cytokines, and lymphokines for rapid degradation. HuR, a ubiquitously expressed member of the embryonic lethal abnormal vision (ELAV) family of RNA-binding proteins, binds ARE sequences an...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16194/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10737787/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.7.3073 |
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