A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Interleukin 17 (IL-17) has been linked to autoimmune diseases, although its regulation and function have remained unclear. Here we have evaluated in vitro and in vivo the requirements for the differentiation of naive CD4 T cells into effector T helper cells that produce IL-17. This process required...

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Main Authors: Park, Heon, Li, Zhaoxia, Yang, Xuexian O, Chang, Seon Hee, Nurieva, Roza, Wang, Yi-Hong, Wang, Ying, Hood, Leroy, Zhu, Zhou, Tian, Qiang, Dong, Chen
Format: Artigo
Language:Inglês
Published: 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618871/
https://ncbi.nlm.nih.gov/pubmed/16200068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1261
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