Ribosomal Mutations Conferring Resistance to Macrolides in Streptococcus pneumoniae Clinical Strains Isolated in Germany

Among a collection of 4,281 pneumococcal isolates, 7 strains isolated in Germany had an unusual macrolide resistance phenotype. The isolates were found to have multiple mutations in the 23S rRNA and alterations in the L4 ribosomal protein. One strain had an amino acid alteration in the L22 ribosomal...

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Bibliographic Details
Main Authors: Reinert, Ralf René, Wild, Angela, Appelbaum, Peter, Lütticken, Rudolf, Cil, Murat Yücel, Al-Lahham, Adnan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC161879/
https://ncbi.nlm.nih.gov/pubmed/12821488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.7.2319-2322.2003
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