Ribosomal Mutations Conferring Resistance to Macrolides in Streptococcus pneumoniae Clinical Strains Isolated in Germany

Among a collection of 4,281 pneumococcal isolates, 7 strains isolated in Germany had an unusual macrolide resistance phenotype. The isolates were found to have multiple mutations in the 23S rRNA and alterations in the L4 ribosomal protein. One strain had an amino acid alteration in the L22 ribosomal...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Reinert, Ralf René, Wild, Angela, Appelbaum, Peter, Lütticken, Rudolf, Cil, Murat Yücel, Al-Lahham, Adnan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12821488/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.7.2319-2322.2003
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