Ribosomal Mutations Conferring Resistance to Macrolides in Streptococcus pneumoniae Clinical Strains Isolated in Germany

Among a collection of 4,281 pneumococcal isolates, 7 strains isolated in Germany had an unusual macrolide resistance phenotype. The isolates were found to have multiple mutations in the 23S rRNA and alterations in the L4 ribosomal protein. One strain had an amino acid alteration in the L22 ribosomal...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Reinert, Ralf René, Wild, Angela, Appelbaum, Peter, Lütticken, Rudolf, Cil, Murat Yücel, Al-Lahham, Adnan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12821488/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.7.2319-2322.2003
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