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Differences in Scrapie-Induced Pathology of the Retina and Brain in Transgenic Mice that Express Hamster Prion Protein in Neurons, Astrocytes, or Multiple Cell Types

Prion protein (PrP) is expressed in many tissues and is required for susceptibility to scrapie and other prion diseases. To investigate the role of PrP expression in different cell types on pathology in retina and brain after scrapie infection, we examined transgenic mice expressing hamster PrP from...

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Main Authors: Kercher, Lisa, Favara, Cynthia, Chan, Chi-Chao, Race, Richard, Chesebro, Bruce
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618708/
https://ncbi.nlm.nih.gov/pubmed/15579448
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