Calpain Mediates Calcium-Induced Activation of the Erk1,2 MAPK Pathway and Cytoskeletal Phosphorylation in Neurons : Relevance to Alzheimer’s Disease

Aberrant phosphorylation of the neuronal cytoskeleton is an early pathological event in Alzheimer’s disease (AD), but the underlying mechanisms are unclear. Here, we demonstrate in the brains of AD patients that neurofilament hyperphosphorylation in neocortical pyramidal neurons is accompanied by ac...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Veeranna, Kaji, Takahide, Boland, Barry, Odrljin, Tatjana, Mohan, Panaiyur, Basavarajappa, Balapal S., Peterhoff, Corrinne, Cataldo, Anne, Rudnicki, Anna, Amin, Niranjana, Li, Bing Sheng, Pant, Harish C., Hungund, Basalingappa L., Arancio, Ottavio, Nixon, Ralph A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618589/
https://ncbi.nlm.nih.gov/pubmed/15331404
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados