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Epigenetic determination of a cell-specific gene expression program by ATF-2 and the histone variant macroH2A

Transcriptional activation of the interleukin-8 (IL-8) gene is restricted to distinct cell types, although the transcriptional regulatory proteins controlling IL-8 gene expression are ubiquitous. We show that cell-specific transcription of IL-8 is due to the distinct chromatin architecture on the en...

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Detalhes bibliográficos
Main Authors: Agelopoulos, Marios, Thanos, Dimitris
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618095/
https://ncbi.nlm.nih.gov/pubmed/17036053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601364
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