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Design of Phase II cancer trials evaluating survival probabilities

BACKGROUND: Phase II cancer studies are undertaken to assess the activity of a new drug or a new treatment regimen. Activity is sometimes defined in terms of a survival probability, a binary outcome such as one-year survival that is derived from a time-to-event variable. Phase II studies are usually...

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Autori principali: Case, L Douglas, Morgan, Timothy M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC161809/
https://ncbi.nlm.nih.gov/pubmed/12697051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-3-6
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