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Human Immunodeficiency Virus Type 1 V1-V2 Envelope Loop Sequences Expand and Add Glycosylation Sites over the Course of Infection, and These Modifications Affect Antibody Neutralization Sensitivity

Over the course of infection, human immunodeficiency virus type 1 (HIV-1) continuously adapts to evade the evolving host neutralizing antibody responses. Changes in the envelope variable loop sequences, particularly the extent of glycosylation, have been implicated in antibody escape. To document mo...

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Detalhes bibliográficos
Main Authors: Sagar, Manish, Wu, Xueling, Lee, Sandra, Overbaugh, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617272/
https://ncbi.nlm.nih.gov/pubmed/16973562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00141-06
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