Selection for Human Immunodeficiency Virus Type 1 Envelope Glycosylation Variants with Shorter V1-V2 Loop Sequences Occurs during Transmission of Certain Genetic Subtypes and May Impact Viral RNA Levels

Designing an effective human immunodeficiency virus type 1 (HIV-1) vaccine will rely on understanding which variants, from among the myriad of circulating HIV-1 strains, are most commonly transmitted and determining whether such variants have an Achilles heel. Here we show that heterosexually acquir...

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Detalhes bibliográficos
Main Authors: Chohan, Bhavna, Lang, Dorothy, Sagar, Manish, Korber, Bette, Lavreys, Ludo, Richardson, Barbra, Overbaugh, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091724/
https://ncbi.nlm.nih.gov/pubmed/15858037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.10.6528-6531.2005
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