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Essential Functions of the Unique N-Terminal Region of the Varicella-Zoster Virus Glycoprotein E Ectodomain in Viral Replication and in the Pathogenesis of Skin Infection

Varicella-zoster virus (VZV) glycoprotein E (gE) is a multifunctional protein important for cell-cell spread, envelopment, and possibly entry. In contrast to other alphaherpesviruses, gE is essential for VZV replication. Interestingly, the N-terminal region of gE, comprised of amino acids 1 to 188,...

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Main Authors: Berarducci, Barbara, Ikoma, Minako, Stamatis, Shaye, Sommer, Marvin, Grose, Charles, Arvin, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617235/
https://ncbi.nlm.nih.gov/pubmed/16973553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00533-06
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