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Differential Requirement for Cell Fusion and Virion Formation in the Pathogenesis of Varicella-Zoster Virus Infection in Skin and T Cells

The protein product of varicella-zoster virus (VZV) ORF47 is a serine/threonine protein kinase and tegument component. Evaluation of two recombinants of the Oka strain, rOka47ΔC, with a C-terminal truncation of ORF47, and rOka47D-N, with a point mutation in the conserved kinase motif, showed that OR...

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Detalhes bibliográficos
Main Authors: Besser, Jaya, Ikoma, Minako, Fabel, Konstanze, Sommer, Marvin H., Zerboni, Leigh, Grose, Charles, Arvin, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524993/
https://ncbi.nlm.nih.gov/pubmed/15542680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.23.13293-13305.2004
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