Dynamics of nascent mRNA folding and RNA–protein interactions: an alternative TAR RNA structure is involved in the control of HIV-1 mRNA transcription

HIV-1 Tat protein regulates transcription elongation by binding to the 59 nt TAR RNA stem–loop structure transcribed from the HIV-1 5′ long terminal repeat (5′-LTR). This established Tat–TAR interaction was used to investigate mRNA folding and RNA–protein interactions during early transcription elon...

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Главные авторы: Richter, Sara N., Bélanger, François, Zheng, Ping, Rana, Tariq M.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2006
Предметы:
RNA
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1616951/
https://ncbi.nlm.nih.gov/pubmed/16920743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl499
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