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TAR RNA loop: A scaffold for the assembly of a regulatory switch in HIV replication

Replication of HIV requires the Tat protein, which activates elongation of RNA polymerase II transcription at the HIV-1 promoter by interacting with the cyclin T1 (CycT1) subunit of the positive transcription elongation factor complex b (P-TEFb). The transactivation domain of Tat binds directly to t...

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Detalhes bibliográficos
Main Authors: Richter, Sara, Ping, Yueh-Hsin, Rana, Tariq M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122997/
https://ncbi.nlm.nih.gov/pubmed/12048247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122119999
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