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Mice deficient in Cu,Zn-superoxide dismutase are resistant to acetaminophen toxicity
Although antioxidants are used to treat an overdose of the analgaesic/antipyretic drug APAP (acetaminophen), roles of antioxidant enzymes in APAP-induced hepatotoxicity remain controversial. Our objective was to determine impacts of knockout of SOD1 (superoxide dismutase; Cu,Zn-SOD) alone or in comb...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1615904/ https://ncbi.nlm.nih.gov/pubmed/16831125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060784 |
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