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The Human Papillomavirus 16 E6 Protein Can Either Protect or Further Sensitize Cells to TNF: Effect of Dose (HPV E6 Sensitizes and Protects Cells from TNF)

High-risk strains of human papillomavirus, including HPV 16, cause human cervical carcinomas, due in part to the activity of their E6 oncogene. E6 interacts with a number of cellular proteins involved in host-initiated apoptotic responses. Paradoxically, literature reports show that E6 can both prot...

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Detalhes bibliográficos
Main Authors: Filippova, Maria, Brown-Bryan, Terry A., Casiano, Carlos A., Duerksen-Hughes, Penelope J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615884/
https://ncbi.nlm.nih.gov/pubmed/15933739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.cdd.4401678
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