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The Full-Length Isoform of Human Papillomavirus 16 E6 and Its Splice Variant E6* Bind to Different Sites on the Procaspase 8 Death Effector Domain

Human papillomavirus 16 is a causative agent of most cases of cervical cancer and has also been implicated in the development of some head and neck cancers. The early viral E6 gene codes for two alternatively spliced isoforms, E6(large) and E6*. We have previously demonstrated the differential effec...

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Autors principals: Tungteakkhun, Sandy S., Filippova, Maria, Fodor, Nadja, Duerksen-Hughes, Penelope J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812347/
https://ncbi.nlm.nih.gov/pubmed/19906919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01331-09
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