The Large and Small Isoforms of Human Papillomavirus Type 16 E6 Bind to and Differentially Affect Procaspase 8 Stability and Activity

Human papillomavirus type 16 (HPV-16) has developed numerous ways to modulate host-initiated immune mechanisms. The HPV-16 E6 oncoprotein, for example, can modulate the cellular level, and consequently the activity, of procaspase 8, thus modifying the cellular response to cytokines of the tumor necr...

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Bibliographic Details
Main Authors: Filippova, Maria, Johnson, Melyssa M., Bautista, Marnelli, Filippov, Valery, Fodor, Nadja, Tungteakkhun, Sandy S., Williams, Kadia, Duerksen-Hughes, Penelope J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Transformation and Oncogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866154/
https://ncbi.nlm.nih.gov/pubmed/17267478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01924-06
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