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The small splice variant of HPV16 E6, E6*, reduces tumor formation in cervical carcinoma xenografts HPV16 E6* reduces tumor formation

High-risk types of human papillomavirus (HPV) cause nearly all cases of cervical cancer. The E6 oncoprotein is produced as a full-length variant (E6) as well as several shorter isoforms (E6*). E6* inhibits certain oncogenic activities of E6, suggesting that it might play an anti-oncogenic role in vi...

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Detalhes bibliográficos
Main Authors: Filippova, Maria, Evans, Whitney, Aragon, Robert, Filippov, Valery, Williams, Vonetta M., Hong, Linda, Reeves, Mark E., Duerksen-Hughes, Penelope
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932372/
https://ncbi.nlm.nih.gov/pubmed/24503078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.12.011
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